Newly Published Study Finds Important Association Between Oxidative Stress, Microvascular Aging and Healing (amazon) (shopzilla)

Miami, Florida (PRWEB) February 06, 2012

A new study, investigating the premature aging and improper healing of the blood vessels, has found that the dysfunction of a cellular factor (Nrf2) to be an underlying cause of the impaired blood vessel formation (angiogenesis) and its subsequent improper healing and premature aging. Expanding on this study, Nutri-Med Logic Corp states that a key target for activation of Nrf2 is to increase the production of an internal anti-oxidant, Glutathione, colloquially referred to as anti-aging anti-oxidant, which decreases by age.

Prior to this new study, the most notable study in premature cellular aging was done by Dr. Farzaneh-Far of San Francisco General Hospital, published in Journal of American Medical Association, where Dr. Farzaneh-Far found an association between the consumption of anti-inflammatory nutrients (Omega-3) and the extreme ends of the DNA (telomeres), as an indicator of pre-mature cellular aging. Accordingly, inflammation was and continue to be presumed as a key culpable element in normal or premature cellular aging.

However, while inflammation exerts itself as a cause but, more often than not, the inflammation could only be the symptom. Thus, distinction has to be made as to whether the cellular premature aging is due to the inflammation, per se, or that the inflammation is a manifestation of another underlying cause Redox Imbalance.

While the lack of anti-inflammatory nutrients could become a causative issue, as to the inflammation, but in the cases of inflammation due to oxidative stress (redox imbalance), anti-inflammatory nutrients could only offer some protective role, whereas improving the redox imbalance would directly address the cause.

This new study correctly brings to surface an important underlying cause of premature aging: Redox Imbalance, which promotes the activation inflammatory genes, via activation of the inflammation master switch (NF-kB).

While this study only discusses the premature cellular aging of the blood vessels but the redox imbalance is a matter of systemic concern, to-wit, not only it affects the cells of the blood vessels but also each and every human cell, as the activation of NF-kB through the redox imbalance is a systemic matter.

As it relates to this study, the genes are those that cause the activation of Nrf2, a cellular transcription factor. Nrf2 targets one of the most important elements in the human anti-oxidant defense (redox): Glutathione. (1)

According to The Department of Internal Medicine of University of Miami, the cellular redox is regulated by three systems, two of which are also regulated by glutathione. (2)

For reason unknown, the production of glutathione decreases by age and while glutathione is found in food, its concentration does not increase significantly either through food or through the dietary supplementation of glutathione.

In 1996, an anti-oxidant researcher at University of Berkeley, California, Dr. Packer, a professor of molecular and cell biology, discovered that R-Alpha Lipoic Acid, a nutrient, increases the production of glutathione.

R-Alpha Lipoic Acid (also known as R-Lipoic Acid) is a biologically significant (active) compound produced by human body and found in many foods. The serum concentration R-Alpha Lipoic Acid, like glutathione, does not increase from food but studies have conclusively shown that the dietary supplementation of R-Alpha Lipoic results in its detectable serum concentration.

In conclusion, Nutri-Med Logic Corp agrees with this important recent study but adds, while targeting the activation of Nrf2 is a fundamental step in correcting the redox imbalance but nutrients that are capable of achieving similar results should receive equal considerations.

Nutri-Med Logic Corp. is a producer dietary supplements such as a Pharmaceutical Grade R-Alpha Lipoic Acid, the dietary supplement of choice for the Diabetics, in Germany for more than 40 years;

Nutri-Med Logic Corp is also the producer of the Natural, Balanced, Deodorized and Concentrated Omega-3, which is also a Pharmaceutical Grade Omega-3;

Producer of PolyEnylPhosphatidylCholine (PPC 425mg), an extract of soy and the recommended dietarty supplement for those with Fatty Liver and Alcoholic Liver Disease, in Europe for about 50 years.

Nutri-Med Logic Corp invites you to visit its News Archives and Review other News Releases on the potential benefits of R-Alpha Lipoic and What Is Omega-3 Good For.

Nutri-Med Logic’s products are Formulated Based on Nutritional Logic, made from the highest quality raw materials that are manufactured in pharmaceutical facilities, encapsulated in pharmaceutical facilities and packaged in pharmaceutical facilities.

It must be noted that the studies, sources or statements above or below have not been evaluated by The FDA and, thus, one should not relate the cause of any diseases, stated herein, to lack of the dietary supplements, stated herein, nor equate their supplementation to prevention, treatment or cure.

1. J Neurochem. 2006 May;97(3):687-96

2. Drugs. 2011 Jul 30;71(11):1385-96

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    A Cross-Sectional Analysis on Deficiency of Choline, a Nutrient, Results in an Important Finding for Postmenopausal Women (amazon) (shopzilla)

    Miami, Florida (PRWEB) February 22, 2012

    The result of a newly published study suggests that postmenopausal women, with an inadequate choline diet, are at higher risk of fibrosis. Nutri-Med Logic Corp adds that in 1998, the Food and Nutrition Board of the Institute of Medicine established a dietary reference intake (DRI) of choline for females based on age, but only from 0 month up to adulthood. The only other distinction, in adult females, was for pregnant or lactating mothers. The US Institute of Medicine did not consider pre or postmenopausal age as criteria for setting a corresponding choline intake.

    The John Hopkins study encompassed 644 subject, which were grouped into children of 9-13 years old, males more than 13 years old, premenopausal women more than 18 years of age and postmenopausal women, taking into account the adequate choline intake as set by US institute of Medicine; Choline deficiency was defined to be at less than 50% of the adequate intake.

    The result of the analysis suggests that postmenopausal women, with fatty liver, having a choline deficient diet had worse fibrosis.

    Nutri-Med Logic Corp adds that this new study correctly opens the discussion, as to whether the Choline adequate intake for females needs to be further examined and additional classification would be appropriate for adult females, to-wit, considering the menopausal stage as a new category and same to be irrespective of the liver health of pre or postmenopausal women.

    It is well established that premenopausal women might be resistant to choline deficiency due to their production of estrogen, which induces synthesis of choline via the PEMT enzyme (FASEB J. 2007 Aug;21(10):2622-32).

    However, given the fact that estrogen levels begin to drop right before, during and after the menopause, further studies might be needed for the adequate choline intake in this category of adult females.

    While this study took into account the fatty liver (non-alcoholic) as a factor in the severity of fibrosis but it is with a doubt that deficiency of choline, by itself, might be a cause of non-alcoholic fatty liver, in the first place.

    Obviously, non-alcoholic fatty liver is associated to variety of factors, but choline deficiency remains as one of the front-runners. A search of PubMed database on choline deficient diet and studies on choline and fatty liver dates back to 1934.

    Furthermore, due to estrogen, physiologically premenopausal women would have a lower choline requirement than men, but with a loss of estrogen at menopausal stage, when taking into account the result of this study, the adequate choline intake for postmenopausal women deserves a new review.

    In conclusion, Nutri-Med Logic Corp agrees with this important study and adds that it might be appropriate to revisit the choline requirement for adult females and re-determine if pre or postmenopausal women would require a separate adequate intake classification.

    Nutri-Med Logic Corp is the producer of PolyEnylPhosphatidylCholine (PPC 425mg), an extract of soy, a pure and effective dietary source of choline and the recommended dietary supplement for those with Fatty Liver and Alcoholic Liver Disease, in Europe for decades.

    Nutri-Med Logic Corp is also the producer of the Natural, Deodorized and Concentrated Omega-3, which is also a Pharmaceutical Grade Omega-3;

    Producer of dietary supplements such as a Pharmaceutical Grade R-Alpha Lipoic Acid, the dietary supplement of choice for the Diabetics, in Germany for decades;

    Nutri-Med Logic Corp invites you to visit its News Archives and Review other News Releases on other potential benefits Poly-Enyl-Phosphatidylcholine and anti-inflammatory nutrients such as Omega-3 and What Is Omega-3 Good For.

    Nutri-Med Logic’s products are Formulated Based on Nutritional Logic, made from the highest quality raw materials that are manufactured in pharmaceutical facilities, encapsulated in pharmaceutical facilities and packaged in pharmaceutical facilities.

    It must be noted that the studies, sources or statements above have not been evaluated by The FDA and, thus, one should not relate the cause of any diseases, stated herein, to lack of the dietary supplements, stated herein, nor equate their supplementation to prevention, treatment or cure.

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      Anti-Aging Site Announces Aging Report After New Brain Study Reveals Important Information on Alzheimers Disease (amazon) (shopzilla)


      Houston, TX. (PRWEB) October 24, 2012

      After a new study done by Washington University School of Medicine in St. Louis revealed new information about the brain when impacted with Alzheimers Disease, AntiAgingProductsReviewed.com announced a new report for those looking to gain insight on preventing the onset of this disease. While the companys primary focus is on preventing all signs of aging, they are announcing this new free informational report to help people get a better understanding of this important part of the aging process. The new reports are aimed to help people understand and possibly prevent the onset of Alzheimer’s disease and were announced after the reveal of this new study brought a great deal of attention to Alzheimers disease.

      The new reviews from Anti Aging Products Reviewed on Alzheimers disease and other aging issues, were inspired by the new study from Washington University which indicated that science doesnt yet understand what causes dementia and that those with Alzheimers disease still have brain plaques in place when suffering from this illness.

      The anti-aging site is launching the new promotion in an attempt to help people understand the severity of Alzheimers disease and how common it is to the aging process. In order to help men and women today that are already worried about physical aging, to help prevent Alzheimers, the professionals at Anti-Aging supplement news have announced their new report offer to any interested individuals.

      To find out more about the company, to view these new reports on Alzheimers disease and to find the best anti-aging solutions available in todays market, visit: http://antiagingproductsreviewed.com/.







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